Neuropharmaceutical Griffonia Seed Extract 5-hydroxytryptophan

Griffonia Seed Extract main ingredient

The main chemical component of Griffonia Seed Extract is 5-hydroxytryptophan, which is a natural amino acid extracted from the dried seeds of the mesquite plant Ghana grain. The chemical name is 5-hydroxy-3-indolyl-α-amino. Propionic acid. Compared with synthetic 5-hydroxytryptophan, its use is safer. People with lower levels of serotonin are more prone to depression, impulsivity and even attack violence. 5-hydroxytryptophan can be converted into 5 by decarboxylation in vivo. -HT, which helps the body to increase 5-HT levels, is an important neuropharmaceutical

1.Antidepressant effect

The experimental observation of the utilization of TRP (tryptophan) in patients with depression found that the utilization of L-TRP in patients with major depression was significantly lower than that in patients with mild depression.

2. Central analgesic effects

TRP may exert central analgesic effects by increasing the central serotonin (5-HT) content. When the 5-HT descending fiber reaches the spinal cord, it can be mediated by interneurons to activate the enkephalin neurons in the keratin region. The latter can inhibit the peripheral pain information transmission to the secondary level by means of presynaptic inhibition. Neurons, thus playing a central analgesic effect.

3. Cardiovascular system effects

The results of animal models of different hypertension in rats indicate that TRP also has antihypertensive activity.

4. Hypnosis

5-hydroxytryptophan can form a neurohormonal precursor serotonin by vitamin B6 in the body, thereby promoting sleep and mental stability.

5. Physiological effects of anti-stress

Studies have found that injection of 5-hydroxytryptophan can reduce the attack and killing of mice in a short period of time, the degree of reduction is proportional to the amount of 5-hydroxytryptophan injection.

6. Effects on neuroendocrine activity

5-hydroxytryptophan can be converted into certain hormones directly involved in endocrine activities, and can also be converted into the central neurotransmitter 5-hydroxytryptamine indirectly affecting the release of neurohormones.