Rhubarb Extract
The plant extract is a dried root and rhizome extract of rhubarb or medicinal rhubarb. The active ingredients are terpenoids, including rhein, emodin, chrysophanol, aloe-emodin, emodin methyl ether, etc., scavenging oxygen free radicals, regulating blood lipids, anti-arteriosclerosis, anti-cancer, anti-aging, anti-psychotic, Antibacterial anti-inflammatory, liver and gallbladder, anti-virus and other effects.
1. Impact on the digestive system
(1) diarrhea: the main site of diarrhea is in the large intestine. The active ingredient in rhubarb is sputum, mainly senna. Senna sputum decomposes under the action of intestinal bacterial enzymes to produce ruthenium ruthenate, which can stimulate the mucosa of the large intestine and increase intestinal peristalsis. In addition, it can inhibit Na+, K+-ATPase on the intestinal cell membrane, hinder Na+ transport, increase intestinal osmotic pressure, retain a large amount of water, and promote intestinal peristalsis and diarrhea.
(2) hepatoprotective effects: Rhubarb extract can promote bile secretion, increase the content of bilirubin and bile acid in bile, relieve bile duct sphincter spasm, enhance duodenal and bile duct dilation, clear bile duct and fine Bile in the bile duct
2. Effects on the blood system
(1) Hemostasis: Rhubarb extract has a hemostatic effect and is effective. The active ingredients are α-catechin and gallic acid. The mechanism of action is to promote the adhesion and aggregation function of platelets; increase the number of platelets and fibrinogen; reduce the activity of antithrombin III; and cause the local blood vessels to contract.
(2) hypolipidemic effect: rhubarb extract can reduce total cholesterol, triglyceride, low density lipoprotein, very low density lipoprotein and lipid peroxide levels. The rhubarb was made into a granule, and even served for 2 months, the lipid-lowering effect was better, and no adverse reactions were observed.
(3) Activating blood: Rhubarb extract has a blood thinning effect, which may be caused by plasma osmotic pressure, which promotes the transfer of extracellular fluid into blood vessels, thereby diluting the blood, resulting in a decrease in blood cells and a decrease in blood viscosity, thereby enhancing micro Circulate to achieve the purpose of promoting blood circulation.
3. Anti-infective effect
Rhubarb extract has inhibitory effects on various Gram-positive and negative bacteria in vitro, especially for Paratyphoid bacillus and Shigella. It also has a certain killing effect on hepatitis B virus, various fungi, amoeba, and vaginal trichomoniasis. The main ingredients of bacteriostatic are rhein, emodin and aloe-emodin. The antibacterial mechanism mainly inhibits the oxidation and dehydrogenation of the intermediates of sugar metabolism, inhibits the synthesis of proteins and nucleic acids, inhibits the bacterial biooxidase system, and induces interferon.
5. Immunomodulatory effects
The effect of rhubarb extract on immune function has two-way regulation, and it has different degrees of immunosuppression. It can inhibit or block cellular immunity and humoral immunity. It can cause immune organs such as thymus, spleen and lymph nodes for a long time. Shrink
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