What is Kojic acid?
Kojic acid is a melanin-specific inhibitor that binds to copper ions in cells after entering the skin cells, alters the steric structure of tyrosinase, and prevents the activation of tyrosinase. Thereby inhibiting the formation of melanin. The kojic acid whitening active agent has better tyrosinase inhibitory effect than other whitening active agents. It does not act on other biological enzymes in the cell, and has no toxic effect on the cells. At the same time, it can enter the intercellular substance to form intercellular gelatin, which plays a role in retaining water and increasing skin elasticity. It has been formulated into various cosmetics to make whitening cosmetics for freckles, age spots, pigmentation and acne.
Application and Function
1.Applied in the field of cosmetics.
In human skin, tyrosine undergoes complex oxidation and polymerization with oxygen radicals under the catalysis of tyrosinase, and finally melanin is synthesized.It can inhibit the synthesis of tyrosinase, so it can strongly inhibit the formation of melanin in the skin, and it is safe and non-toxic, and does not produce leukoplakia sequelae. Therefore, It has been formulated into lotion, mask, lotion and skin cream. It can effectively treat high-grade whitening cosmetics such as freckles, age spots, pigmentation and acne. Kojic acid at a concentration of 20ug/ml can inhibit 70-80% of the activity of various tyrosinases (or polyphenol oxidases PPO), and the amount of addition in cosmetics is generally 0.5-2.0%.
2.Food processing field.
It can be used as a food additive to maintain freshness, antisepsis and anti-oxidation. Experiments have shown that it can inhibit the conversion of sodium nitrite into carcinogenic nitrosamines in bacon, and the addition of kojic acid in food does not affect the taste, aroma and texture of food; it is also the production of maltol and ethyl maltol. Raw materials, in food processing, it has a wide range of applications.
3.The field of medicine.
Because kojic acid has no mutagenic effect on eukaryotic cells, it can eliminate free radicals and enhance white blood cell kinetics in human body, which is beneficial to human health. Therefore, kojic acid has been used as a raw material for cephalosporin antibiotics, and the finished drug is used for treatment. Headache, toothache and local inflammation, etc., analgesic and anti-inflammatory effects are ideal
4. In the agricultural field.
It can be used to produce biopesticide. Adding bio-fertilizer (dark-red liquid) made of 0.5-1.0% kojic acid, whether it is sprayed at a low concentration as a foliar fertilizer, or made into a growth-increasing agent for root application, this crop production accelerator for food and Vegetables have obvious yield-increasing effects.
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