Hops extract Introduction
Hops extract was extracted from the female inflorescence of the mulberry plant hop Humulus lupulus L. It has anti-tumor, anti-oxidation, anti-bacterial, anti-free radicals and other functions, can be used as a food additive to prevent food spoilage, and can be used as antioxidants in medicine, cosmetics, health foods and foods.
Antibacterial effect
Hops extract, hopsone, and valerone can inhibit the growth of Gram-positive bacteria, such as Bacillus anthracis, Bacillus cereus, diphtheria, pneumococci, Staphylococcus aureus, etc.; Negative bacteria have no inhibitory effect, can also inhibit tuberculosis, and have weak or ineffective effects on pathogenic and non-pathogenic fungi and actinomycetes. The inhibitory effect of hemp ketone on Gram-positive bacteria or tuberculosis is stronger than that of humulone. The residue after removing hopsone and humulones from the hop extract still has antibacterial effect. The hopsone has good fat solubility, large distribution coefficient, and easy to enter the wax film of Mycobacterium tuberculosis and plays a special affinity. In vitro, its inhibition of Mycobacterium tuberculosis has no synergistic effect with streptomycin. Penicillin slightly enhances its inhibition of Staphylococcus aureus, and erythromycin can be enhanced by 4 times.
Sedation
The hop extract can be calmed at low doses, the middle dose can be hypnotized, and the large dose causes paralysis, and the sleep time caused by it begins to be slow, but lasting.
Estrogen-like effects
The hop extract has a strong estrogen-like effect, and the hop estrogen activity mainly comes from the β-acid fraction in the resin, while the α-acid fraction has no such effect
Anti-oxidize effect
The anti-oxidation effect of hops aqueous extract showed that the anti-oxidation effect of hops aqueous extract was close to vitamin C, and it was dose-effect relationship, and the antioxidant content of hops was thermostable. It can be seen that hop is a good natural resistance. Oxidizing substances. The main active constituents of antioxidants in hops are α-acid, β-acid, extract and bitter water (ie, tetrahydroisomerized extract obtained by catalytic hydrogenation of hops), which have a certain scavenging effect on superoxide anion radicals. Among them, the bitter water is the strongest, the α-acid and the extract are slightly inferior, and the β-acid is hardly soluble in the test solution and no result is obtained.
Anti-radiation effect
The effect of total flavonoids of hops on the number of white blood cells in irradiated mice was determined. The results showed that the protective effect of the total flavonoids in the spleen and thymus of the squid on the spleen and thymus of the geranium was equivalent to that of the ginkgo biloba. The protective effect of the high dose group was better than other group.
Inhibit obesity
The study examined the anti-obesity effects of hop extracts on male mice fed high-fat diet, high-fat diet plus 2% or 5% hop extract for 20 weeks. The results showed that hop extract can inhibit weight gain and adipose tissue weight gain, adipocyte diameter and high fat diet-induced increase in liver lipids.
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